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What’s Niacinamide?

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As busy mamas, we don’t have plenty of time to dedicate to our skincare routines. That’s why it’s nice to have some “go-to” pure magnificence merchandise that maximize our time and provides us nice advantages—ones that not solely give us glowing skin however are additionally fast and simple to make use of. 

Niacinamide is one skincare ingredient I like to recommend making part of your pure skincare routine.

What Is Niacinamide?

This nutrient, additionally known as nicotinamide, is among the types of vitamin B3, niacin. It’s a water-soluble vitamin that’s found in meat within the type of niacinamide and plant meals as nicotinic acid. 

As a result of niacin is water-soluble, we want it day by day. Water-soluble nutritional vitamins are absorbed shortly and are usually not saved by our our bodies, so we have to replenish them every day.

What Is Niacinamide Good for? 

The physique wants it to transform the meals you eat into vitality. Niacin additionally helps with vital processes within the physique, like creating hormones. It’s an important nutrient for metabolism, which implies it’s additionally vital for the expansion and restore of the physique’s tissues.

That’s particularly evident in its skill to advertise well-nourished, lovely pores and skin. In spite of everything, skincare starts on the inside with good diet. 

Learn how to Get Niacinamide

Niacin and niacinamide are extensively present in meals and are sometimes added to fortified grain merchandise to make sure we get the advisable quantity—round 14-18 mg per day. Additionally it is out there in complement type. You can too use it topically (as a lotion, gel, or serum) for a wide range of skincare considerations. 

Niacinamide in Meals

Purple meat, hen, and fish are some meals with the very best quantities of this vitamin, together with peanuts and low. Barley, wheat, beans, soybeans, potatoes, and rice have reasonable quantities, whereas vegetables and fruit have decrease quantities. 

You probably have a compromised gut, you will have a tough time absorbing niacinamide from meals, and dietary supplements could also be extra useful to get the quantity you want.

Niacin (additionally known as nicotinic acid) may cause a “niacin flush” due to its results on blood vessel capillaries. It causes the capillaries to increase shortly, rising the blood stream to the pores and skin’s floor, which causes redness, heat, and itchiness in that space of the pores and skin. That’s why I desire the niacinamide type of this B-vitamin.

Niacinamide in Supplementation

A niacinamide nutritional supplement could assist enhance pores and skin circumstances, shield the pancreas in Kind 1 diabetes, and assist the kidneys. 

In addition to supporting kidney and pancreatic well being, the primary well being advantage of taking this complement pertains to pores and skin well being:

  • Anti-inflammatory – when taken as a complement and utilized to the pores and skin. A review study discovered it to be useful in each pimples and rosacea.
  • Lowering pimples – and breakouts (which I nonetheless get every now and then). 
  • Anti-aging – helps sluggish the getting old course of and has an anti-aging effect
  • Protecting towards pores and skin most cancers – A 2015 study printed within the New England Journal of Medication discovered that supplementing (500 mg twice day by day) lowered precancerous pores and skin injury in individuals who had been recognized with pores and skin most cancers up to now 5 years. 

Niacinamide in Skincare

Many merchandise use niacinamide as a skincare ingredient. Yow will discover it in cleansers, toners, gels, serums, lotions, eye lotions, and moisturizers. It helps with many various elements of pores and skin well being, together with enhancing the pores and skin barrier, hydration, night out pores and skin tone, and defending towards injury. 

Skincare merchandise like cleansers and makeup removers that wash off most likely don’t supply sufficient contact time along with your pores and skin to make a lot of an impression. It’s higher to make use of merchandise that keep on the pores and skin, like serums, moisturizers, or lotions.

Dermatologists advocate a topical utility of niacinamide for some particular pores and skin points in addition to basic skincare. Listed below are some particular issues that it helps with:  


Hyperpigmentation is a situation the place you develop darker patches in your pores and skin and is attributable to the pores and skin creating extra melanin. In a clinical study printed within the British Journal of Dermatology, a gaggle used niacinamide moisturizer for 4 weeks and located that hyperpigmentation considerably decreased.


A 2011 review study notes that dermatologists have used nicotinamide for over 40 years for rosacea and different pores and skin circumstances. A randomized controlled trial carried out in 2005 examined a moisturizer in sufferers with rosacea. The cream, utilized twice day by day for 4 weeks, improved the pores and skin barrier and improved the situation in rosacea victims.

Dry Pores and skin

Dry pores and skin could be a difficulty as we age or based mostly on the local weather that we dwell in. You probably have dry pores and skin, you may wish to strive it. A study of sufferers with dry pores and skin who utilized nicotinamide cream twice day by day to their face over 4 or eight weeks confirmed a big lower within the lack of moisture within the pores and skin and an enchancment of their dry pores and skin situation.


This skincare ingredient may assist with pimples and blemishes. In decreasing the severity of pimples circumstances, one study of 4% nicotinamide gel discovered it was similar to a 1% clindamycin gel (the usual antibiotic therapy). 

Anti-Getting old (advantageous strains and wrinkles)

In a study of 50 women with indicators of getting old (together with advantageous strains and wrinkles), a 5% concentrated product was utilized to half of their face twice day by day for 12 weeks. On the opposite half of their face, they used a placebo product. 

On the finish of the research, the perimeters of the faces that used the therapy confirmed vital enchancment general, together with a discount in advantageous strains and wrinkles, extra even pores and skin tone, improved coloration (much less yellowing), and higher elasticity. 

Pores and skin Most cancers

Niacinamide’s anti-aging results may additionally assist forestall pores and skin most cancers. In a 2019 study printed within the Worldwide Journal of Molecular Science, researchers identified that getting old is a serious threat issue for the event of pores and skin most cancers.

The physique wants niacinamide to supply NAD+, a coenzyme that protects the pores and skin from gene-damaging toxins. When genes are broken, it could possibly lead down a path towards most cancers. The depletion of NAD+ in our our bodies is usually related to the illnesses of getting old, which embody most cancers.

That’s the place replenishing niacinamide within the pores and skin, whether or not via dietary supplements or skincare merchandise, may also help preserve pores and skin wholesome and youthful. 

What Is Niacinamide Serum?

A serum is a lightweight, quick-absorbing skincare product that delivers a concentrated dose of niacinamide. The focus within the gel-like liquid could be anyplace from 2% to 10%. A typical dosage is 4%.

When used topically, this nutrient may also help promote the expansion of the pores and skin’s ceramide (lipid) barrier. This helps forestall water loss and retain moisture.

Niacinamide is useful for all skin types, whether or not your pores and skin is oily, dry, or a mixture. Should you’re involved about delicate pores and skin, it is rather soothing, so long as there aren’t different components within the product that may irritate your pores and skin. 

When in search of a skincare product, like a cleanser, serum, or gel, take note of what else is in it. You’ll wish to make sure that it’s freed from parabens, phthalates, and artificial fragrances. 

If you wish to make your individual skincare product with niacinamide, right here’s a recipe for a DIY silky moisturizer I really like!

Learn how to Use a Serum

It’s greatest to make use of the serum after cleaning, firming, and exfoliating. Then you may work with a clear palate. Apply it evenly over your face moderately than simply utilizing it on the right track/drawback areas. 

Observe up your niacinamide product with any moisturizers or sunscreen merchandise you wish to apply.

It’s an ingredient you need to use year-round. You gained’t have points making use of it earlier than going within the solar, and there’s no cause to take breaks except you’re experiencing unintended effects.

Dangers & Facet Results 

There are just a few potential dangers or unintended effects to contemplate when utilizing this highly effective B vitamin: 

Inside Dietary supplements

Potential unintended effects of taking dietary supplements embody:

  • Abdomen upset
  • Fuel
  • Dizziness
  • Rash or itchy pores and skin

These aren’t widespread, however should you begin experiencing a few of these shortly after including a complement type, strive eradicating it and see if the signs enhance. 

Taking excessive amounts over time might result in diabetes, Parkinson’s illness, and liver injury. You’ll wish to make sure that your vitamin B ranges are inside a standard vary while you get your yearly bloodwork finished. 

Topical Niacinamide

Potential unintended effects from utilizing a topical model are normally noticeable straight away and embody: 

  • Gentle redness 
  • Itching 
  • Slight burning sensation

Should you use a focus of 5% or underneath, these are typically unusual and gentle once they happen. Larger concentrations usually tend to create points.

FAQs: Can You Combine Niacinamide and _________?

As you’re placing collectively your pure skincare routine, you may surprise about combining totally different merchandise or components. I’ll cowl just a few of these frequently-combined components beneath and the very best order to make use of them so that you get probably the most out of them.

Niacinamide & Retinol Serum

Retinol is a standard antioxidant serum used on the face. Retinol is stronger than nicotinamide and is thought to trigger irritation, dry pores and skin, and redness. You should utilize retinol and niacinamide concurrently, however ideally, you’d apply retinol first and comply with it with niacinamide. It is because the retinol tends to be a bit irritating to the pores and skin, and following up with niacinamide helps soothe the pores and skin and assist it to heal. 

Learn this post to be taught extra about retinol/retinoids. Bear in mind that retinoids could trigger solar sensitivity, although. 

Niacinamide & Vitamin C Serum

If utilizing a vitamin C serum, apply it at a unique time than the niacinamide skincare product. It will possibly forestall the vitamin C serum from working because it ought to, inactivating it. If uncovered to warmth, vitamin C could react with niacinamide, turning it into niacin (nicotinic acid) and aggravating the pores and skin. 

Ideally, use the niacinamide serum within the morning and the vitamin C serum at night time.

Niacinamide & Hyaluronic Acid

Hyaluronic acid is one other skincare ingredient that may pair properly with niacinamide. Each work so as to add moisture to the pores and skin, decrease irritation, stimulate collagen production, and customarily promote therapeutic. 

These two components are sometimes discovered collectively in skincare merchandise. They complement moderately than compete, and every enhances the opposite’s moisturizing properties. The hyaluronic acid is nice for enhancing moisture and tightening the pores and skin, and the niacinamide provides a beautiful pure radiance.

If utilized individually, use the hyaluronic acid first since it could possibly draw water into the pores and skin, conserving it moist all day. Then add the niacinamide, which helps shield the pores and skin’s floor and maintains a wholesome degree of pure oils.

Niacinamide & Salicylic Acid 

Salicylic acid can work properly alongside niacinamide, as it really works as an astringent, cleaning out the pores and serving to to deal with pimples. Niacinamide then provides again the moisture that the drying, typically irritating salicylic acid could take away.

Should you use them collectively, apply the salicylic acid first after which use the niacinamide serum.

This text was medically reviewed by Madiha Saeed, MD, a board-certified household doctor. As all the time, this isn’t private medical recommendation and we advocate that you simply discuss along with your physician.

Have you ever tried niacinamide skincare merchandise? How does it give you the results you want? Do you mix it with different serums or components like those talked about? 

  1. Institute of Medication (US) Standing Committee on the Scientific Analysis of Dietary Reference Intakes and its Panel on Folate, Different B Nutritional vitamins, and Choline. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington. (DC): Nationwide Academies Press (US); 1998. 6, Niacin.
  2. Hill, L. J., & Williams, A. C. (2017). Meat Consumption and the Dose of Vitamin B3 – Nicotinamide: Cause of the Causes of Disease Transitions, Health Divides, and Health Futures?. Worldwide journal of tryptophan analysis : IJTR, 10, 1178646917704662.
  3. Ods.od.nih.gov. 2011. Office of Dietary Supplements – Niacin.
  4. Jacobson T. A. (2010). A “hot” topic in dyslipidemia management–“how to beat a flush”: optimizing niacin tolerability to promote long-term treatment adherence and coronary disease prevention. Mayo Clinic proceedings, 85(4), 365–379. https://www.mayoclinicproceedings.org/article/S0025-6196(11)60429-1/fulltext
  5. Hegyi, J., Schwartz, R. A., & Hegyi, V. (2004). Pellagra: dermatitis, dementia, and diarrhea. Worldwide journal of dermatology, 43(1), 1–5. 
  6. Niren N. M. (2006). Pharmacologic doses of nicotinamide in the treatment of inflammatory skin conditions: a review. Cutis, 77(1 Suppl), 11–16.
  7. Surjana, D., & Damian, D. L. (2011). Nicotinamide in dermatology and photoprotection. Skinmed, 9(6), 360–365.
  8. Ying W. (2008). NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxidants & redox signaling, 10(2), 179–206. 
  9. Chen, A. C., Martin, A. J., Choy, B., Fernández-Peñas, P., Dalziell, R. A., McKenzie, C. A., Scolyer, R. A., Dhillon, H. M., Vardy, J. L., Kricker, A., St George, G., Chinniah, N., Halliday, G. M., & Damian, D. L. (2015). A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention. The New England journal of drugs, 373(17), 1618–1626. 
  10. Hakozaki, T., Minwalla, L., Zhuang, J., Chhoa, M., Matsubara, A., Miyamoto, Ok., Greatens, A., Hillebrand, G. G., Bissett, D. L., & Boissy, R. E. (2002). The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. The British journal of dermatology, 147(1), 20–31.
  11. Draelos, Z. D., Ertel, Ok., & Berge, C. (2005). Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea. Cutis, 76(2), 135–141.
  12. Soma, Y., Kashima, M., Imaizumi, A., Takahama, H., Kawakami, T., & Mizoguchi, M. (2005). Moisturizing effects of topical nicotinamide on atopic dry skin. Worldwide journal of dermatology, 44(3), 197–202.
  13. Shalita, A. R., Smith, J. G., Parish, L. C., Sofman, M. S., & Chalker, D. Ok. (1995). Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris. Worldwide journal of dermatology, 34(6), 434–437.
  14. Bissett, D. L., Rectangular, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic surgical procedure : official publication for American Society for Dermatologic Surgical procedure [et al.], 31(7 Pt 2), 860–865.
  15. Fania, L., Mazzanti, C., Campione, E., Candi, E., Abeni, D., & Dellambra, E. (2019). Role of Nicotinamide in Genomic Stability and Skin Cancer Chemoprevention. Worldwide journal of molecular sciences, 20(23), 5946.Rolfe H. M. (2014). A review of nicotinamide: treatment of skin diseases and potential side effects. Journal of beauty dermatology, 13(4), 324–328.

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